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Center for Neurogenetics

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Faculty & Research

Researchers with the Center for Neurogenetics seek to understand genetic and epigenetic influences on early brain development and related disorders (such as spina bifida, brain malformation, developmental delay, autism spectrum, and epilepsy), and on adult-onset disorders (such as Alzheimer’s and other dementias, Parkinson's, ataxias, demyelinating disorders, and epilepsy). 

Center researchers focus on:

  • Identifying new single-gene mutations, genetic variation patterns, and/or network interactions associated with neuropsychiatric disease
  • Investigating non-protein-coding genome regions that regulate gene expression related to neurobiology
  • Developing new approaches for identifying deleterious genome sequence and structure variants and how they impact brain formation and function across the lifespan
  • Investigating the epigenetic influences on genome function in neuropsychiatric disorders and how environment impacts the reading of the genetic code that drives the systems biology of the brain

You can learn more about our faculty and their research through the links below.

Basic Mechanism Research
M. Elizabeth Ross, M.D., Ph.D.

M. Elizabeth Ross, M.D., Ph.D.

  • Feil Family Brain & Mind Research Institute Department of Neurology
  • Director, Center for Neurogenetics

Research Interest: Genetic and molecular biological bases of neurological diseases of children and adults

Lab Page | VIVO
Jacqueline Burre

Jacqueline Burré, Ph.D.

  • Feil Family Brain & Mind Research Institute
  • Appel Institute for Alzheimer's Research

Research Interest: Disorders of synaptic function related to infantile epilepsies, neurodegenerative disorders including Lewy body dementia and Parkinson's disease

Lab Page | VIVO
Dilek Colak

Dilek Colak, Ph.D.

  • Feil Family Brain & Mind Research Institute
  • Center for Neurogenetics

Research Interest: Molecular and cellular alterations underlying cognitive disorders such as autism and schizophrenia with a special focus on subcellular localization and regulation of RNA

Lab Page | VIVO
Natalia Gracia de Marco

Natalia De Marco García, Ph.D.

  • Feil Family Brain & Mind Research Institute
  • Center for Neurogenetics

Research Interest: Experience-dependent interneuron development in the juvenile and adult brain in health and disease.

Lab Page | VIVO
Rebecca Jones

Rebecca Jones, Ph.D.

  • Department of Psychiatry
  • Sackler Institute for Developmental Psychobiology

Research Interest: Development of the human social brain, and how and why this differs in those with autism spectrum disorders and typically developing individuals

Lab Page | VIVO
Francis Lee, M.D., Ph.D.

Francis Lee, M.D., Ph.D.

  • Department of Psychiatry
  • Sackler Institute for Developmental Psychobiology

Research Interest: Genetic mouse models to delineate the role of growth factors, such as BDNF, in complex behaviors related to the pathophysiology and treatment of major depression and other affective disorders

Lab Page | VIVO
Conor Liston

Conor Liston, M.D., Ph.D.

  • Feil Family Brain & Mind Research Institute
  • Center for Neurogenetics
  • Department of Psychiatry

Research Interest: Synaptic network remodeling in relation to stress, sleep, adolescent development, and emerging psychiatric disorders

Lab Page | VIVO
Anna Orr

Anna Orr, Ph.D.

  • Feil Family Brain & Mind Research Institute
  • Appel Institute for Alzheimer's Research

Research Interest: Glial communication and mitochondrial signaling as a therapeutic target to prevent or ameliorate neurodegeneration and brain dysfunction

Lab Page | VIVO
Manu Sharma

Manu Sharma, Ph.D.

  • Feil Family Brain & Mind Research Institute
  • Appel Institute for Alzheimer's Research

Research Interest: Protein-protein interactions and dysfunctions related to Alzheimer's disease and Parkinson's disease

Lab Page | VIVO
Hagen Tilgner, Ph.D.

Hagen Tilgner, Ph.D.

  • Feil Family Brain & Mind Research Institute
  • Center for Neurogenetics

Research Interest: Information processing of the genome through regulation of transcriptional isoforms

Lab Page | VIVO
Bioinformatics and Genomics Research
Chris Mason

Christopher E. Mason, Ph.D.

  • Institute for Computational Biology
  • Department of Physiology and Biophysics

Research Interest: Exploration of systems-based computational methods to enable an understanding of the functional elements of the human genome, such that we can begin to repair or re-engineer these genetic networks for disease prevention and treatment

Lab Page | VIVO
Vanessa Aguiar-Pulido, Ph.D.

Vanessa Aguiar-Pulido, Ph.D.

  • Feil Family Brain & Mind Research Institute
  • Center for Neurogenetics

Research Interest: Computational life sciences, biomedical data science and machine learning as applied to neurological diagnosis and therapeutics.

Lab Page | VIVO
Olivier Elemento

Olivier Elemento, Ph.D.

  • Institute for Computational Biology
  • Department of Physiology and Biophysics

Research Interest: Computational systems biology and precision medicine

Lab Page | VIVO
Clinical Research
M. Elizabeth Ross, M.D., Ph.D.

M. Elizabeth Ross, M.D., Ph.D.

  • Feil Family Brain & Mind Research Institute Department of Neurology
  • Director, Center for Neurogenetics

Research Interest: Genetic and molecular biological bases of neurological diseases of children and adults

Lab Page | VIVO
Christopher McCord Cunniff, M.D.

Christopher McCord Cunniff, M.D.

  • Department of Pediatrics
  • Director, Medical Genetics Division in Pediatrics

Research Interest: Medical genetic diagnosis and the clinical delineation of malformation and neurogenetic syndromes

POPS Profile | VIVO
Matthew Fink

Matthew Fink, M.D.

  • Chairman, Department of Neurology

Research Interest: Neurocritical care and vascular diseases affecting the brain

POPS Profile | Lab Page | VIVO
Claire Henchcliffe

Claire Henchcliffe, M.D., Ph.D.

  • Department of Neurology
  • Parkinson's Disease and Movement Disorders Institute

Research Interest: Biomarker development for early diagnosis, assessment of prognosis, and clinical research of movement disorders, including Parkinson’s, dystonia, and other conditions

POPS Profile | VIVO
Richard Isaacson

Richard Isaacson, M.D.

  • Department of Neurology
  • Director, Alzheimer's Disease and Memory Disorders Program

Research Interest: Providing the latest evidence-based and comprehensive management options for treatment, as well as to reduce risk

POPS Profile | VIVO
Barry Kosofsky

Barry Kosofsky, M.D., Ph.D.

  • Department of Pediatrics
  • Director, Pediatric Neurology

Research Interest: Neurogenetic disorders of childhood, gene therapy for Batten's disease, phenotype and genotype of autism spectrum disorders.

POPS Profile | VIVO
Eric Mallack

Eric J. Mallack, M.D.

  • Department of Pediatrics
  • Pediatric Neurology and Neurogenetics
  • K12-NSADA Research Scholar

Research Interest: Leukodystrophy and genetic leukoencephalopathy, gene therapy for X-Linked Adrenoleukodystrophy, advanced neuroimaging, undiagnosed neurogenetic disorders

POPS Profile | VIVO
Devorah Segal, M.D., Ph.D.

Devorah Segal, M.D., Ph.D.

  • Department of Pediatrics
  • Pediatric Neurology and Neurogenetics

Research Interest: Improving capabilities for clinical diagnosis and management of children with rare and complex neurogenetic and neurodevelopmental disorders

POPS Profile | VIVO
Timothy Vartanian, M.D., Ph.D.

Timothy Vartanian, M.D., Ph.D.

  • Professor of Neuroscience
  • Professor of Neurology
  • Attending Neurologist, NewYork-Presbyterian Hospital

Research Interest: Molecular basis of new lesion formation in Multiple Sclerosis, oligodendrocyte development and myelination, and the mechanisms of myelin regeneration in demyelinating diseases

POPS Profile | VIVO
Headshot of Mary Vo

Mary Vo, M.D.

Research Interest:  Chronic inflammatory demyelinating neuropathy at the Peripheral Neuropathy Center

VIVO
Genetic Counseling
Shenela Lakhani, M.Sc., CGC, CCGC

Shenela Lakhani, M.Sc., CGC, CCGC

  • Director of Genetic Counseling, Instructor of Neuroscience
  • Feil Family Brain & Mind Research Institute
  • Center for Neurogenetics

Research Interest: Accelerating advances in medical genetic information management and patient communication

VIVO
Headshot of Tess Levy

Tess Levy M.Sc., CGC

  • Genetic Counselor
  • Feil Family Brain & Mind Research Institute
  • Center for Neurogenetics

Research Interest: Improving quality of care and overall patient outcomes through the provision of comprehensive patient-centered genetic services and promotion of interdisciplinary and interprofessional collaboration throughout the healthcare continuum.   

Headshot of Denise  Ma

Denise Ma

  • Research Assistant
  • Feil Family Brain & Mind Research Institute
  • Center for Neurogenetics

Research Interest: Administration and coordination of clinical care provision with an emphasis on advancing the overall clinical and research objectives of the Center for Neurogenetics through patient communication and care management.

Weill Cornell Medicine
Center for Neurogenetics
413 East 69th Street, Box 240 New York, NY 10021 Phone: (646) 962-6144 Fax: (646) 962-0104